List of matches in this round
- TimeMatch
- September 1, 2022
- 6:00 pmSeminoles8 - 34NFC Eagles
- September 7, 2022
- 6:00 pmSeminoles6 - 16Holy Comforter Crusaders
- September 20, 2022
- 6:00 pmFranklin County Seahawks62 - 20Seminoles
- September 22, 2022
- 6:00 pmSeminoles22 - 29Maclay Mauraders
- October 4, 2022
- 6:00 pmHoly Comforter Crusaders26 - 6Seminoles
- October 11, 2022
- 6:00 pmSeminoles8 - 46Franklin County Seahawks